Aetiology and natural history of primary sclerosing cholangitis--a decade of progress?
نویسنده
چکیده
منابع مشابه
Primary sclerosing cholangitis: etiopathogenesis and clinical management.
Primary sclerosing cholangitis (PSC) is a chronic inflammatory liver disease characterized by the destruction of medium to large-sized bile ducts and intense, concentric fibrosis. Complications from PSC include bacterial cholangitis, cirrhosis, and cholangiocarcinoma and a therapy that might alter the natural history of the disease remains lacking. Our understanding of the pathogenesis of PSC a...
متن کاملImproving Symptoms of Primary Sclerosing Cholangitis by Iranian Traditional Medicine
Introduction: Primary Sclerosing Cholangitis (PSC) is a chronic cholestatic disease that results from the inflammation and destruction of intra- and extra-hepatic bile ducts and fibrosis which can lead to cirrhosis. The purpose of this report is to provide the clinical experience of Iranian traditional medicine with the best therapeutic effect within the shortest time. <s...
متن کاملNatural history of low grade dysplasia in patients with primary sclerosing cholangitis and ulcerative colitis.
BACKGROUND AND AIM Patients with ulcerative colitis (UC) and primary sclerosing cholangitis (PSC) are at increased risk of colon cancer. The aim of this study was to determine the natural history of LGD and its progression to high grade dysplasia (HGD)/colorectal cancer (CRC) in PSC-UC patients. METHODS Ten PSC-UC patients with LGD who underwent surveillance colonoscopy from 1996 to 2011 were...
متن کاملAutoimmune liver disease in children.
Autoimmune liver disorders are characterised by an inflammatory liver histology, circulating non-organ specific autoantibodies and increased levels of immunoglobulin G (IgG) in the absence of a known aetiology. They respond to immunosuppressive treatment, which should be instituted as soon as diagnosis is made. Liver disorders with a likely autoimmune pathogenesis include autoimmune hepatitis (...
متن کاملLiver disease in women: the influence of gender on epidemiology, natural history, and patient outcomes.
Women more commonly present with acute liver failure, autoimmune hepatitis, benign liver lesions, primary biliary cirrhosis, and toxin-mediated hepatotoxicity. Women less commonly have malignant liver tumors, primary sclerosing cholangitis, and viral hepatitis. There is a decreased rate of decompensated cirrhosis in women with hepatitis C virus infection, no survival difference in alcohol-relat...
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ورودعنوان ژورنال:
- Gut
دوره 32 12 شماره
صفحات -
تاریخ انتشار 1991